Determination of deoxycholic acid pool size and input rate using [24-13C]deoxycholic acid and serum sampling.
We have developed an isotope dilution method for determination of deoxycholic acid pool size and input rate which employs oral administration of 50 mg of [24-13C]deoxycholic acid and serum sampling.The method has been validated by classical isotope dilution technique majicontrast red using [24-14C]deoxycholic acid and bile sampling in five patients